RSPO1 anticorps (AA 206-240)

N° du produit ABIN6244080

Détail du produit anti-RSPO1 anticorps

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Épitope: AA 206-240

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RSPO1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RSPO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 206-240 amino acids from human RSPO1.

Clone: RB54226

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur RSPO1

Antigène: RSPO1 (R-Spondin 1 (RSPO1))

Autre désignation: RSPO1 (RSPO1 Produits)

Synonymes: anticorps RGD1565558, anticorps CRISTIN3, anticorps RSPO, anticorps R-spondin, anticorps Rspondin, anticorps wu:fj81e05, anticorps zgc:92153, anticorps R-spondin 1, anticorps Rspo1, anticorps RSPO1, anticorps LOC100049655, anticorps rspo1

Sujet: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

Poids moléculaire: 28959

UniProt: Q2MKA7