Septin 2 anticorps (AA 112-361)

N° du produit ABIN6147552

L’anticorps Lapin Polyclonal anti-Septin 2 a été validé pour WB et IF. Il convient pour détecter Septin 2 dans des échantillons de Humain.

Aperçu rapide pour Septin 2 anticorps (AA 112-361) (ABIN6147552)

Antigène: Septin 2 (SEPT2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Septin 2 anticorps

Épitope: AA 112-361

Séquence: RDCFKTIISY IDEQFERYLH DESGLNRRHI IDNRVHCCFY FISPFGHGLK PLDVAFMKAI HNKVNIVPVI AKADTLTLKE RERLKKRILD EIEEHNIKIY HLPDAESDED EDFKEQTRLL KASIPFSVVG SNQLIEAKGK KVRGRLYPWG VVEVENPEHN DFLKLRTMLI THMQDLQEVT QDLHYENFRS ERLKRGGRKV ENEDMNKDQI LLEKEAELRR MQEMIARMQA QMQMQMQGGD GDGGALGHHV

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 112-361 of human Septin 2 (NP_004395.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Septin 2

Antigène: Septin 2 (SEPT2)

Autre désignation: 2-Sep

Sujet: Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.,SEPT2,DIFF6,NEDD-5,NEDD5,Pnutl3,hNedd5,septin-2,Cell Biology & Developmental Biology,Cell Cycle,Immunology & Inflammation,Cytokines,2-Sep

Poids moléculaire: 41 kDa/42 kDa/45 kDa

ID gène: 4735

UniProt: Q15019