AMPD3 anticorps (CF®405S)

N° du produit ABIN6155505

Cet anticorps Souris Monoclonal détecte spécifiquement AMPD3 dans IF, ICC, FACS et IHC (f). Il présente une réactivité envers Humain.

Aperçu rapide pour AMPD3 anticorps (CF®405S) (ABIN6155505)

Antigène: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AMPD3 est conjugé à/à la CF®405S

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: AMPD3-901

Détail du produit anti-AMPD3 anticorps (CF®405S)

Fonction: Mouse Monoclonal anti-Adenosine Monophosphate Deaminase-3 (AMPD3) (AMPD3/901), CF405S Conjugate

Attributs du produit: This antibody recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human AMDP3 protein

Isotype: IgG2b kappa

Information d'application

Indications d'application: Immunohistology formalin-fixed 2-4 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunocytochemistry 1-2.0 μg/mL
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 1-2 μg/million cells in 0.1 mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

RBC. Fetal liver, Spleen or Placenta

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur AMPD3

Antigène: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Autre désignation: Adenosine Monophosphate Deaminase-3 (AMPD3)

Poids moléculaire: 90 kDa

ID gène: 272, 501890

UniProt: Q01432