ADRP anticorps (AA 249-376) (CF®488A)

N° du produit ABIN6155755

L’anticorps Souris Monoclonal anti-ADRP a été validé pour IHC, ELISA, IF et Coat. Il convient pour détecter ADRP dans des échantillons de Humain.

Aperçu rapide pour ADRP anticorps (AA 249-376) (CF®488A) (ABIN6155755)

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADRP est conjugé à/à la CF®488A

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat)

Clone: ADFP-1366

Détail du produit anti-ADRP anticorps (CF®488A)

Épitope: AA 249-376

Fonction: Mouse Monoclonal anti-Adipophilin / Perilipin-2 (ADFP/1366), CF488A Conjugate

Attributs du produit: This antibody recognizes a protein of 48 kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human Adipophilin protein fragment (aa249-376) (exact sequence is proprietary)

Isotype: IgG2b kappa

Information d'application

Indications d'application: Immunohistology (formalin) 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Immunofluorescence 0.5-1 μg/mL
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Commentaires:

HepG2 or JAR cells. Liver, Adrenal gland or Cerebellum.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur ADRP

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Autre désignation: Adipophilin / Perilipin-2

Sujet: Adipophilin, ADFP, Adipose differentiation-related protein (ADRP), Perilipin-2 (PLIN2)

Poids moléculaire: 48 kDa

ID gène: 123, 3416

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism