CD80 anticorps (CF®488A)

N° du produit ABIN6156553

L’anticorps Souris Monoclonal anti-CD80 a été validé pour FACS, ELISA, IF et Coat. Il convient pour détecter CD80 dans des échantillons de Humain.

Aperçu rapide pour CD80 anticorps (CF®488A) (ABIN6156553)

Antigène: CD80

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD80 est conjugé à/à la CF®488A

Application: Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Coating (Coat)

Clone: C80-1608

Détail du produit anti-CD80 anticorps (CF®488A)

Fonction: Mouse Monoclonal anti-CD80 (C80/1608), CF488A Conjugate

Attributs du produit: T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells and bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31 % overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human full-length CD80 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunofluorescence 1-2 μg/mL

• Flow Cytometry 0.5-1 μg/million cells
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Commentaires:

Raji or Ramos Cells. Tonsil, Spleen or Thymus

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur CD80

Antigène: CD80

Autre désignation: CD80

Poids moléculaire: 60 kDa

ID gène: 941, 838

UniProt: P33681

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints