CD47 anticorps (CF®647)
Aperçu rapide pour CD47 anticorps (CF®647) (ABIN6159731)
Antigène
Voir toutes CD47 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Mouse Monoclonal anti-CD47 (IAP/964 + B6H12.2), CF647 Conjugate
-
Attributs du produit
- This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogène
- Recombinant human IAP protein (IAP/964), Intact CD47 purified from placenta (B6H12.2)
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
-
Commentaires
-
HUVEC, OVCA3 cells, Placenta, Brain and Ovarian Tumors
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 100 μg/mL
-
Buffer
- PBS/0.1 % BSA/0.05 % azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Protect from light
-
-
- CD47
-
Autre désignation
- CD47
-
Sujet
- Antigenic Surface Determinant Protein OA3, IAP, Integrin Associated Protein, Integrin Associated Signal Transducer, MER6, OA3, Protein MER6, Rh Related Antigen
-
Poids moléculaire
- ~50 kDa
-
ID gène
- 961, 446414
-
UniProt
- Q08722
Antigène
-