JUP anticorps

N° du produit ABIN6164928

Cet anticorps Souris Monoclonal détecte spécifiquement JUP dans WB, IF et FACS. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Poulet, Chien, Boeuf (Vache) et Cat.

Aperçu rapide pour JUP anticorps (ABIN6164928)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Souris, Rat, Poulet, Chien, Boeuf (Vache), Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 15F11

Détail du produit anti-JUP anticorps

Fonction: Mouse Monoclonal anti-Catenin, gamma (15F11), Purified, BSA-free

Attributs du produit: This antibody recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (?, ?, ? and ?) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. ? T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. ? T-catenin binds to ? E-catenin as well as to ?-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for ?-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogène: full length chicken Catenin gamma protein|Recombinant

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

A431, T47D or MCF-7 cells. Skin

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Agent conservateur: Azide free

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: Catenin, gamma

Sujet: ARVD12, Catenin (cadherin-associated protein), gamma 80  kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB

Poids moléculaire: 80-87 kDa

ID gène: 3728, 514174

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location