CD44 anticorps (APC)

N° du produit ABIN616786

Cet anticorps Souris Monoclonal détecte spécifiquement CD44 dans FACS. Il présente une réactivité envers Humain, Chien et Porc.

Aperçu rapide pour CD44 anticorps (APC) (ABIN616786)

Antigène: CD44

Reactivité: Humain, Chien, Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: MEM-263

Détail du produit anti-CD44 anticorps (APC)

Specificité: This antibody reacts with extracellular (N-terminal) domain of standard CD44 (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.), it is negative on platelets and hepatocytes.

Réactivité croisée (Details): Species reactivity (tested):Human, Porcine and Canine (Dog)

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline (PBS) containing 15 mM Sodium Azide and 0.2 % (w/v) high-grade protease free BSA as a stabilizing agent

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

ID gène: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling