MMP2 anticorps (AA 444-575) (CF®594)
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- Antigène Voir toutes MMP2 Anticorps
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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Épitope
- AA 444-575
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MMP2 est conjugé à/à la CF®594
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Fonction
- Mouse Monoclonal anti-MMP2 / Collagenase-Type-IV-A (MMP2/1501), CF594 Conjugate
- Attributs du produit
- This antibody recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant human MMP2 protein fragment (aa444-575) (exact sequence is proprietary)
- Clone
- MMP2-1501
- Isotype
- IgG1
- Top Product
- Discover our top product MMP2 Anticorps primaire
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- Indications d'application
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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U-138 MG or U-87 MG cells. Placenta
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- MMP2 (Matrix Metalloproteinase 2 (MMP2))
- Autre désignation
- MMP2 / Collagenase-Type-IV-A (MMP2 Produits)
- Synonymes
- anticorps 2-MMP, anticorps CG1794, anticorps DM2-MMP, anticorps Dm2-MMP, anticorps Dmel\\CG1794, anticorps MMP2, anticorps anon-WO0118547.84, anticorps dm-2MMP, anticorps dmmp2, anticorps l(2)02353, anticorps mmp2, anticorps wu:fa99h12, anticorps wu:fk89d01, anticorps fgmmp-2, anticorps Mmp-2, anticorps LOC100135793, anticorps Clg4a, anticorps GelA, anticorps MMP-2, anticorps CLG4, anticorps CLG4A, anticorps MMP-II, anticorps MONA, anticorps TBE-1, anticorps matrix metallopeptidase 2, anticorps Matrix metalloproteinase 2, anticorps matrix metalloproteinase 2, anticorps matrix metalloproteinase-2, anticorps MMP2, anticorps Mmp2, anticorps mmp2, anticorps LOC657982, anticorps LOC100135793
- Sujet
- 72 kD type IV collagenase|CLG4A|Collagenase Type 4 alpha|Collagenase type IV A|Gelatinase A|Gelatinase alpha|Gelatinase neutrophil|Matrix metalloproteinase-2|MMP2|MONA|Neutrophil gelatinase|PEX|TBE-1
- Poids moléculaire
- 72 kDa (Pro), 63 kDa (cleaved)
- ID gène
- 4313, 513617
- UniProt
- P08253
- Pathways
- Activation of Innate immune Response
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