HTR2C anticorps (AA 439-460)

N° du produit ABIN617931

Cet anticorps anti-HTR2C est un anticorps Lapin Polyclonal détectant HTR2C dans WB, IHC, IF, ICC et IEM. Adapté pour Souris et Rat. Ce Primary Antibody a été cité dans 4+ publications.

Aperçu rapide pour HTR2C anticorps (AA 439-460) (ABIN617931)

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HTR2C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)

Détail du produit anti-HTR2C anticorps

Épitope: AA 439-460

Réactivité croisée: Humain, Souris, Rat (Rattus)

Attributs du produit: The 5-HT 2C Receptor Antibody was raised against synthetic peptide sequence corresponding to amino acids 439-460 of the rat 5-HT2C receptor coupled to KLH and bovine thyroglobulin. The 5-HT2C receptor antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat choroid plexus and hippocampus using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are /500 - 1/1000 in PBS - Bn/Av-HRP technique. Intensification methods such as nickel will approximately double the dilution factor as recommended. The antibody was characterized by immunohistochemistry and Western blot. Western blotting revealed a single band of approximately 70 kD. Preincubation of the antibody with an excess of the synthetic peptide blocked staining. Immunohistochemical staining of rat brain correlates well with Northern analysis, in situ hybridization and receptor autoradiography. BlastP database sequence homology searches confirmed that this sequence is unique to rat, mouse and human 5-HT2C receptors.

Purification: Affinity Purified

Immunogène: Rat 5-HT2C receptor (439-460)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Contains ≤ 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.

Références pour anticorps anti-HTR2C (ABIN617931)

Zhang, Li, Xin, Lao, Ren, Berman, Tan, Zhang: "Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model." dans: Neurochemical research, Vol. 36, Issue 10, pp. 1785-92, (2011) (PubMed).

Coulon, Kanyshkova, Broicher, Munsch, Wettschureck, Seidenbecher, Meuth, Offermanns, Pape, Budde: "Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling." dans: Frontiers in cellular neuroscience, Vol. 4, pp. 132, (2011) (PubMed).

Yang, Mahaffey, Bérubé, Maddatu, Cox, Frankel: "Complex seizure disorder caused by Brunol4 deficiency in mice." dans: PLoS genetics, Vol. 3, Issue 7, pp. e124, (2007) (PubMed).

Holmes: "5-Hydroxytryptamine2C receptors on pudendal motoneurons innervating the external anal sphincter." dans: Brain research, Vol. 1057, Issue 1-2, pp. 65-71, (2005) (PubMed).

Détails sur HTR2C

Antigène: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Autre désignation: Serotonin Receptor 2C (HTR2C)

Sujet: Other Names:
5-hydroxytryptamine receptor 2C,5-HT2C, 5HT-1C, 5-HTR2C,5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled

ID gène: 25187

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour