TGF-beta anticorps (CF®568)

N° du produit ABIN6180696

Cet anticorps Souris Monoclonal détecte spécifiquement TGF-beta dans Neut et Func. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Hamster et Singe.

Aperçu rapide pour TGF-beta anticorps (CF®568) (ABIN6180696)

Antigène: TGF-beta (TGFb)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Hamster, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGF-beta est conjugé à/à la CF®568

Application: Neutralization (Neut), Functional Studies (Func)

Clone: 1D11-16-8

Détail du produit anti-TGF-beta anticorps (CF®568)

Fonction: Mouse Monoclonal anti-TGF-beta (1D11.16.8), CF568 Conjugate

Attributs du produit: This MAb recognizes TGF beta 1, 2 and 3. Three TGF? ?s have been identified in mammals. TGF? ?1, TGF? ?2 and TGF? ?3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF? ? requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF? ?3 protein has approximately 80 % identity to the mature region of both TGF? ?1 and TGF? ?2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity. TGF? ?'s inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. See the < a href="https://biotium.com/wp-content/uploads/2013/07/CF-dye-selection-guide.pdf" target="_blank" rel="noopener">CF® Dye Selection Guide for more information. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Bovine TGF-beta2 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Cytokine neutralization or functional assay, order Ab without BSA/azideOptimal dilution for a specific application should be determined by user

Commentaires:

Salivary gland carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur TGF-beta

Antigène: TGF-beta (TGFb)

Autre désignation: TGF-beta

Sujet: GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41

Poids moléculaire: ~13 kDa

ID gène: 7040, 7042, 7043

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus