Recombinant Cadherin-16 anticorps (CF®594)

N° du produit ABIN6182948

Cet anticorps anti-Cadherin-16 est un anticorps Souris Monoclonal détectant Cadherin-16 dans IHC, IF et FACS. Adapté pour Humain, Souris, Rat, Chien et Lapin.

Aperçu rapide pour Recombinant Cadherin-16 anticorps (CF®594) (ABIN6182948)

Antigène: Cadherin-16 (CDH16)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Chien, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cadherin-16 est conjugé à/à la CF®594

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: RCDH16-1071

Détail du produit anti-Cadherin-16 anticorps (CF®594)

Fonction: Recombinant Mouse Monoclonal Ksp-Cadherin / CDH16 (rCDH16/1071), CF594 Conjugate

Attributs du produit: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human CDH16 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunohistology (formalin) 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA Buffer  pH 9.0for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Normal kidney or renal cell carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: Ksp-Cadherin / CDH16

Sujet: Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody

Poids moléculaire: 130 kDa

ID gène: 1014, 513660

UniProt: O75309