Cyclin H anticorps

N° du produit ABIN6241261

Cet anticorps anti-Cyclin H est un anticorps Souris Monoclonal détectant Cyclin H dans WB et IP. Adapté pour Humain.

Aperçu rapide pour Cyclin H anticorps (ABIN6241261)

Antigène: Cyclin H (CCNH)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cyclin H est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-Cyclin H anticorps

Immunogène: Recombinant Protein

Information d'application

Indications d'application: IP: 1:500. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C,-20 °C

Détails sur Cyclin H

Antigène: Cyclin H (CCNH)

Autre désignation: Cyclin H

Sujet: Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

UniProt: P51946

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase