NGFR anticorps (C-Term)

N° du produit ABIN6242228

Cet anticorps Lapin Polyclonal détecte spécifiquement NGFR dans WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour NGFR anticorps (C-Term) (ABIN6242228)

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NGFR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB53297

Détail du produit anti-NGFR anticorps

Épitope: AA 276-310, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NGFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 276-310 amino acids from the C-terminal region of human NGFR.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur NGFR

Antigène: NGFR (Nerve Growth Factor Receptor (NGFR))

Autre désignation: NGFR

Sujet: Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.

Poids moléculaire: 45183

UniProt: P08138

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding