DMBT1 anticorps (AA 2160-2192)

N° du produit ABIN6242287

Cet anticorps anti-DMBT1 est un anticorps Lapin Polyclonal détectant DMBT1 dans WB. Adapté pour Rat.

Aperçu rapide pour DMBT1 anticorps (AA 2160-2192) (ABIN6242287)

Antigène: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMBT1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB53896

Détail du produit anti-DMBT1 anticorps

Épitope: AA 2160-2192

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DMBT1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2160-2192 amino acids from human DMBT1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur DMBT1

Antigène: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Autre désignation: DMBT1

Sujet: May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly- sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH -dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.

Poids moléculaire: 260735

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response