Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

DPPA3 anticorps (C-Term)

DPPA3 Reactivité: Souris WB Hôte: Lapin Polyclonal RB51138 unconjugated
N° du produit ABIN6242289
  • Antigène Voir toutes DPPA3 Anticorps
    DPPA3 (Developmental Pluripotency Associated 3 (DPPA3))
    Épitope
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 134-170, C-Term
    Reactivité
    • 20
    • 11
    • 1
    • 1
    Souris
    Hôte
    • 20
    • 1
    • 1
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DPPA3 est non-conjugé
    Application
    • 8
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This mouse Dppa3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 134-170 amino acids from the C-terminal region of mouse Dppa3.
    Clone
    RB51138
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DPPA3 Anticorps primaire
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    DPPA3 (Developmental Pluripotency Associated 3 (DPPA3))
    Autre désignation
    Dppa3 (DPPA3 Produits)
    Synonymes
    anticorps STELLA, anticorps 2410075G02Rik, anticorps PCG7, anticorps PGC7, anticorps Stella, anticorps developmental pluripotency associated 3, anticorps developmental pluripotency-associated 3, anticorps DPPA3, anticorps Dppa3
    Sujet
    Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis.
    Poids moléculaire
    17670
    UniProt
    Q8QZY3
Vous êtes ici:
Support technique