Lamin A/C anticorps (AA 465-498)

N° du produit ABIN6242430

L’anticorps Lapin Polyclonal anti-Lamin A/C a été validé pour WB. Il convient pour détecter Lamin A/C dans des échantillons de Humain.

Aperçu rapide pour Lamin A/C anticorps (AA 465-498) (ABIN6242430)

Antigène: Lamin A/C (LMNA)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin A/C est non-conjugé

Application: Western Blotting (WB)

Clone: RB48839

Détail du produit anti-Lamin A/C anticorps

Épitope: AA 465-498

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LMNA(Lamin-A/C) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 465-498 amino acids from the Central region of human LMNA(Lamin-A/C).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:500. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur Lamin A/C

Antigène: Lamin A/C (LMNA)

Autre désignation: LMNA(Lamin-A/C)

Sujet: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation. Required for osteoblastogenesis and bone formation. Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone.

Poids moléculaire: 74139

UniProt: P02545

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus