Nicastrin anticorps (AA 99-133)

N° du produit ABIN6242494

Cet anticorps anti-Nicastrin est un anticorps Lapin Polyclonal détectant Nicastrin dans WB. Adapté pour Humain et Rat.

Aperçu rapide pour Nicastrin anticorps (AA 99-133) (ABIN6242494)

Antigène: Nicastrin (NCSTN)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nicastrin est non-conjugé

Application: Western Blotting (WB)

Clone: RB53031

Détail du produit anti-Nicastrin anticorps

Épitope: AA 99-133

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This NCSTN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from human NCSTN.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:8000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur Nicastrin

Antigène: Nicastrin (NCSTN)

Autre désignation: NCSTN

Sujet: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.

Poids moléculaire: 78411

UniProt: Q92542

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway