RNF139 anticorps (AA 604-636)

N° du produit ABIN6242550

L’anticorps Lapin Polyclonal anti-RNF139 a été validé pour WB. Il convient pour détecter RNF139 dans des échantillons de Humain.

Aperçu rapide pour RNF139 anticorps (AA 604-636) (ABIN6242550)

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF139 est non-conjugé

Application: Western Blotting (WB)

Clone: RB54248

Détail du produit anti-RNF139 anticorps

Épitope: AA 604-636

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RNF139 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 604-636 amino acids from human RNF139.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur RNF139

Antigène: RNF139 (Ring Finger Protein 139 (RNF139))

Autre désignation: RNF139

Sujet: E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.

Poids moléculaire: 75994

UniProt: Q8WU17