Serotonin Receptor 1A anticorps (AA 239-273)

N° du produit ABIN6242991

L’anticorps anti-Serotonin Receptor 1A Polyclonal Lapin est utilisé pour la détection de Serotonin Receptor 1A dans des échantillons de Humain. Il a été validé pour WB et FACS.

Aperçu rapide pour Serotonin Receptor 1A anticorps (AA 239-273) (ABIN6242991)

Antigène: Serotonin Receptor 1A (HTR1A)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB46792

Détail du produit anti-Serotonin Receptor 1A anticorps

Épitope: AA 239-273

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HTR1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 239-273 amino acids from the Central region of human HTR1A.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Autre désignation: HTR1A

Sujet: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5- hydroxytryptamine release and in the regulation of dopamine and 5- hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Poids moléculaire: 46107

UniProt: P08908

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour