Serotonin Receptor 1A anticorps (AA 301-400)

N° du produit ABIN738006

Cité dans 3 publications. Cet anticorps anti-Serotonin Receptor 1A Polyclonal Lapin (ABIN738006) détecte spécifiquement Serotonin Receptor 1A dans WB, IF (cc), IF (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour Serotonin Receptor 1A anticorps (AA 301-400) (ABIN738006)

Antigène: Serotonin Receptor 1A (HTR1A)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Serotonin Receptor 1A anticorps

Épitope: AA 301-400

Fonction: 5HT1A Receptor Polyclonal Antibody

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat 5-HTR1A

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Serotonin Receptor 1A (ABIN738006)

García-Pedraza, Fernández-González, López, Martín, Alarcón-Torrecillas, Rodríguez-Barbero, Morán, García-Domingo: "Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes." dans: Life sciences, Vol. 293, pp. 120335, (2022) (PubMed).

Yeh, Weng, Chang, Chan, Huang, Chu, Wei, Ma, Cheng, Ma, Chen, Shyu: "Calcitonin alleviates hyperalgesia in osteoporotic rats by modulating serotonin transporter activity." dans: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Vol. 27, Issue 11, pp. 3355-3364, (2016) (PubMed).

Zhou, Wu, Zhou, Liu, Lee, Liu, Devkota, Ro, Zhu, Suh: "Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(-/-) mice." dans: Translational psychiatry, Vol. 6, Issue 6, pp. e836, (2016) (PubMed).

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Autre désignation: 5-HTR1A

Sujet:

Synonyms: 5HT1A, RAT5HT1A, 5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, Serotonin receptor 1A, Htr1a

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

ID gène: 24473

UniProt: P19327

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour