Serotonin Receptor 1A anticorps (AA 301-400)

N° du produit ABIN738006

Détail du produit anti-Serotonin Receptor 1A anticorps

Antigène: Serotonin Receptor 1A (HTR1A)

Épitope: AA 301-400

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat 5-HTR1A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Serotonin Receptor 1A (ABIN738006)

García-Pedraza, Fernández-González, López, Martín, Alarcón-Torrecillas, Rodríguez-Barbero, Morán, García-Domingo: "Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes." dans: Life sciences, Vol. 293, pp. 120335, (2022) (PubMed).

Yeh, Weng, Chang, Chan, Huang, Chu, Wei, Ma, Cheng, Ma, Chen, Shyu: "Calcitonin alleviates hyperalgesia in osteoporotic rats by modulating serotonin transporter activity." dans: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Vol. 27, Issue 11, pp. 3355-3364, (2016) (PubMed).

Zhou, Wu, Zhou, Liu, Lee, Liu, Devkota, Ro, Zhu, Suh: "Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(-/-) mice." dans: Translational psychiatry, Vol. 6, Issue 6, pp. e836, (2016) (PubMed).

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Autre désignation: 5-HTR1A (HTR1A Produits)

Synonymes: anticorps 5-HT-dro2A, anticorps 5-HT1ADro, anticorps 5-HT[1A]Dro, anticorps 5-HT[[1ADro]], anticorps 5-HT[[1A]], anticorps 5-HT[[1A]]DRO, anticorps 5HT-R2A, anticorps 5HT-dro2A, anticorps 5HT-drp[[2A]], anticorps 5HT1A, anticorps 5HT[[1ADro]], anticorps 5htdro2a, anticorps CG16720, anticorps DRO2A, anticorps Dm5HTdro2A, anticorps Dmel\\CG16720, anticorps d5-HT1A, anticorps 5htr1a, anticorps htr1a, anticorps HTR1A, anticorps Htr1a, anticorps 5-Ht1a, anticorps Gpcr18, anticorps 5-HT-1A, anticorps 5-HT1A, anticorps 5HT1a, anticorps ADRB2RL1, anticorps ADRBRL1, anticorps G-21, anticorps PFMCD, anticorps RAT5HT1A, anticorps 5ht1a, anticorps adrb2rl1, anticorps adrbrl1, anticorps htr1a-A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, anticorps 5-hydroxytryptamine receptor 1A, anticorps 5-hydroxytryptamine (serotonin) receptor 1A a, anticorps 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog, anticorps 5-HT1A, anticorps HTR1A, anticorps htr1aa, anticorps Htr1a, anticorps htr1a.L

Sujet:

Synonyms: 5HT1A, RAT5HT1A, 5-hydroxytryptamine receptor 1A, 5-HT-1A, 5-HT1A, Serotonin receptor 1A, Htr1a

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

ID gène: 24473

UniProt: P19327

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour