PRKAB1 anticorps

N° du produit ABIN6243028

Cet anticorps anti-PRKAB1 Monoclonal Souris (Clone 1420CT832-86-25) (ABIN6243028) détecte spécifiquement PRKAB1 dans WB. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour PRKAB1 anticorps (ABIN6243028)

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Reactivité: Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRKAB1 est non-conjugé

Application: Western Blotting (WB)

Clone: 1420CT832-86-25

Détail du produit anti-PRKAB1 anticorps

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This PRKAB1 antibody is generated from a mouse immunized with a recombinant of human PRKAB1.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PRKAB1

Antigène: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Autre désignation: PRKAB1

Sujet: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Poids moléculaire: 30382

UniProt: Q9Y478

Pathways: AMPK Signaling, L'effet Warburg