JUP anticorps
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- Antigène Voir toutes JUP Anticorps
- JUP (Junction Plakoglobin (JUP))
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Reactivité
- Humain, Souris, Rat, Poulet, Boeuf (Vache), Chien, Cat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp JUP est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Purification
- Protein G affinity chromatography
- Immunogène
- Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.
- Clone
- 15F11
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product JUP Anticorps primaire
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- Indications d'application
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Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunoprecipitation: suitable
The stated application concentrations are suggested starting amounts. Titration of the Plakoglobin antibody may be required due to differences in protocols and secondary/substrate sensitivity. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Antigène
- JUP (Junction Plakoglobin (JUP))
- Autre désignation
- Gamma Catenin (JUP Produits)
- Synonymes
- anticorps ARVD12, anticorps CTNNG, anticorps DP3, anticorps DPIII, anticorps PDGB, anticorps PKGB, anticorps arvd12, anticorps ctnng, anticorps dp3, anticorps dpiii, anticorps pdgb, anticorps pkgb, anticorps plak, anticorps D930025P04Rik, anticorps PG, anticorps cb80, anticorps danPG, anticorps fb11b06, anticorps jup, anticorps wu:fb11b06, anticorps junction plakoglobin, anticorps junction plakoglobin L homeolog, anticorps Junction plakoglobin, anticorps junction plakoglobin a, anticorps junction plakoglobin S homeolog, anticorps JUP, anticorps Jup, anticorps jup, anticorps jup.L, anticorps Tsp_06656, anticorps plak, anticorps jupa, anticorps jup.S
- Sujet
- Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]
- ID gène
- 3728
- UniProt
- P14923
- Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location
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