Cadherin-16 anticorps

N° du produit ABIN6252615

Cet anticorps Lapin Polyclonal détecte spécifiquement Cadherin-16 dans IF, FACS et IHC (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Cadherin-16 anticorps (ABIN6252615)

Antigène: Cadherin-16 (CDH16)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin-16 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Cadherin-16 anticorps

Purification: Protein A affinity chromatography

Immunogène: A recombinant human protein was used as the immunogen for the Cadherin 16 antibody.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/10e6 cells

Immunofluorescence: 1-2 μg/mL

Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

Optimal dilution of the Cadherin 16 antibody to be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur Cadherin-16

Antigène: Cadherin-16 (CDH16)

Autre désignation: Cadherin 16

Sujet: Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that CDH16 (kidney-specific cadherin, Cadherin 16) is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, CDH16 is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. CDH16 has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

ID gène: 1014

UniProt: O75309