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HLA-ABC anticorps

Cet anticorps Souris Monoclonal détecte spécifiquement HLA-ABC dans FACS, IF et WB. Il présente une réactivité envers Humain, Souris et Non-Human Primate.
N° du produit ABIN6252708

Aperçu rapide pour HLA-ABC anticorps (ABIN6252708)

Antigène

Voir toutes HLA-ABC Anticorps
HLA-ABC

Reactivité

  • 80
  • 28
  • 21
  • 19
  • 17
  • 13
  • 13
  • 12
  • 11
  • 11
  • 7
  • 7
  • 6
  • 5
  • 2
  • 1
Humain, Souris, Non-Human Primate

Hôte

  • 67
  • 10
  • 4
Souris

Clonalité

  • 71
  • 9
Monoclonal

Conjugué

  • 31
  • 8
  • 8
  • 7
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp HLA-ABC est non-conjugé

Application

  • 64
  • 19
  • 17
  • 13
  • 10
  • 9
  • 9
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Clone

246-B8-E7
  • Purification

    Protein G affinity chromatography

    Immunogène

    Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.

    Isotype

    IgG2a kappa
  • Indications d'application

    Western blot: 1-2 μg/mL

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.2 mg/mL

    Buffer

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Antigène

    HLA-ABC

    Autre désignation

    HLA-ABC

    Sujet

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    UniProt

    P01889, P30443, P30499

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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