Retinoblastoma Protein (Rb) anticorps

N° du produit ABIN6252811

L’anticorps Souris Monoclonal anti-Retinoblastoma Protein (Rb) a été validé pour WB, IP et IHC (p). Il convient pour détecter Retinoblastoma Protein (Rb) dans des échantillons de Humain et Souris.

Aperçu rapide pour Retinoblastoma Protein (Rb) anticorps (ABIN6252811)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoblastoma Protein (Rb) est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1-1754

Détail du produit anti-Retinoblastoma Protein (Rb) anticorps

Purification: Protein G affinity chromatography

Immunogène: A human recombinant protein was used as the immunogen for this Rb antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 0.5-1 μg/mL

IP: 1-2 μg/500 μg protein lysate

IHC (FFPE): 1-2 μg/mL for 30 min at RT

Titering of the Rb antibody may be required for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur Retinoblastoma Protein (Rb)

Antigène: Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))

Autre désignation: Retinoblastoma / Rb

Sujet: Recognizes a 105  kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It reacts with the hyper-phosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.

ID gène: 5925

UniProt: P06400

Pathways: Mitotic G1-G1/S Phases