ITGAL anticorps

N° du produit ABIN6252976

Cet anticorps anti-ITGAL Monoclonal Souris (Clone TS1-22) (ABIN6252976) détecte spécifiquement ITGAL dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ITGAL anticorps (ABIN6252976)

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ITGAL est non-conjugé

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: TS1-22

Détail du produit anti-ITGAL anticorps

Fonction: CD11a Unconjugated Antibody

Attributs du produit: The clone recognizes a 170-180 kD alpha chain of a type I transmembrane glycoprotein also known as CD11a or LFA-1a. It is also known as LFA-1α. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. CD11a is abundantly expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils but does not express by the non-hematopoietic tissues and platelets. Up-regulation of CD11a on activated lymphocytes is required to induce their immune response. Absence or reduced CD11a expression on tumor cells helps to escape from regular immune surveillance and it may be one of reason of in vivo tumor generation.

Purification: Purified

Pureté: >95 %

Immunogène: Human HLA-DRCTL line cytolytic Tlymphocytes

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur ITGAL

Antigène: ITGAL (Integrin alpha-L (ITGAL))

Autre désignation: CD11a

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex