CD4 anticorps (iFluor™700)
Aperçu rapide pour CD4 anticorps (iFluor™700) (ABIN6253114)
Antigène
Voir toutes CD4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD4 iFluor™ 700 Antibody
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Attributs du produit
- CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. The OKT4 binds to the D3 domain of CD4 and does not inhibit HIV binding.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- Human peripheral blood T lymphocytes
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD4
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Autre désignation
- CD4
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NCBI Accession
- NM_000616
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UniProt
- P01730
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Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Antigène
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