Cathepsin D anticorps (C-Term)

N° du produit ABIN6254162

Il existe 1 publication pour ce produit. L’anticorps anti-Cathepsin D Polyclonal Chèvre est utilisé pour la détection de Cathepsin D dans des échantillons de Humain, Souris, Rat, Singe, Hamster, Boeuf (Vache), Porc, Lapin, Chien, Cheval, Cobaye, Avian, Cat, Poulet, Âne, Chévre et Mouton. Il a été validé pour WB, IF, IHC (p), IHC (fro) et IEM.

Aperçu rapide pour Cathepsin D anticorps (C-Term) (ABIN6254162)

Antigène: Cathepsin D (CTSD)

Reactivité: Humain, Souris, Rat, Singe, Hamster, Boeuf (Vache), Porc, Lapin, Chien, Cheval, Cobaye, Avian, Cat, Poulet, Âne, Chévre, Mouton

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin D est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoelectron Microscopy (IEM)

Détail du produit anti-Cathepsin D anticorps

Épitope: C-Term

Fonction: Anti-Cathepsin D

Séquence: DQVEVASGLT LCKEGCEAIV DTGTSLMVGP VDEVRELQKA IGAVPLIQGE YMIPCEKVST LPAITLKLGG KGYKLSPEDY TLKVSQAGKT LCLSGFMGMD IPPPSGPLWI LGDVFIGRYY TVFDRDNNRV GFAEAARL

Specificité: This antibody gives a positive signal in the following human (Jurkat, HT1080, HUH, MDA-MB-231, ARPE19, SH-SY5Y), canine (MDCK) and monkey (COS-7) whole cell lysates.

Attributs du produit: Cathepsin D

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 275 aa to the C-terminus of human Cathepsin D produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: WB:1:250-1:1,000, IF:1:50-1:200, IHC-P:1:200-1:1,000, IHC-F:1:200-1:1,000, IEM:1:50-1:200

Restrictions: For Research Use only

Stockage

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-Cathepsin D (ABIN6254162)

Pelkonen, Sato, Reinisalo, Kidron, Tachikawa, Watanabe, Uchida, Urtti, Terasaki: "LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line." dans: Molecular pharmaceutics, Vol. 14, Issue 3, pp. 605-613, (2017) (PubMed).

Détails sur Cathepsin D

Antigène: Cathepsin D (CTSD)

Autre désignation: Cathepsin D

Sujet:

Goat polyclonal antibody to Cathepsin D. Cathepsin D is a lysosomal aspartic protease of the pepsin family. Acid protease active in intracellular protein breakdown. It is composed of a dimer of disulphide-linked heavy and light chains, both produced from a single protein precursor. It is involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

ceroid-lipofuscinosis, CLN10, CPSD, CTSD, lysosomal aspartyl protease, lysosomal aspartyl peptidase, neuronal 10 antibody.

Pathways: Peptide Hormone Metabolism