ErbB2/Her2 anticorps (C-Term)

N° du produit ABIN6254225

L’anticorps anti-ErbB2/Her2 Polyclonal Chèvre est utilisé pour la détection de ErbB2/Her2 dans des échantillons de Humain, Souris, Rat, Chien, Singe, Cheval, Porc, Lapin, Boeuf (Vache), Hamster, Avian, Cat, Poulet, Âne, Chévre, Cobaye et Mouton. Il a été validé pour WB, IHC (p) et IHC (fro).

Aperçu rapide pour ErbB2/Her2 anticorps (C-Term) (ABIN6254225)

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reactivité: Humain, Souris, Rat, Chien, Singe, Cheval, Porc, Lapin, Boeuf (Vache), Hamster, Avian, Cat, Poulet, Âne, Chévre, Cobaye, Mouton

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ErbB2/Her2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ErbB2/Her2 anticorps

Épitope: C-Term

Fonction: Anti-ERBB2

Séquence: MPHPPPAFSP AFDNLYYWDQ DPPERGAPPS TFKGTPTAEN PEYLGLDVPV

Specificité: Detects endogenous levels of ERBB2 by Western blot.

Attributs du produit: Erb-b2 receptor tyrosine kinase

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide derived from within residues 1,177 aa to the C-terminus of human ERBB2 produced in E. coli.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Stockage

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Détails sur ErbB2/Her2

Antigène: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Autre désignation: ERBB2

Sujet:

Goat polyclonal antibody to ERBB2. This protein is a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases containing a single transmembrane domain and has an approximate molecular weight of 185 kDa. ERBB2 contains no ligand binding domain and interacts with other EGF receptor family members to form a heterodimer, stabilize ligand binding, and enhance kinase-mediated downstream signalling. It has been shown to be involved in embryonic development and cancer progression.

CD340, erb-b2 receptor tyrosine kinase 2, HER2, HER-2, HER-2/neu, MLN 19, NEU, NGL and TKR1 antibody.

Poids moléculaire: 185 kDa

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development