CD4 anticorps

N° du produit ABIN6254232

Cité dans 1 publication. Cet anticorps anti-CD4 Polyclonal Chèvre (ABIN6254232) détecte spécifiquement CD4 dans WB, IHC (fro) et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Poulet, Singe, Chien, Porc, Lapin, Boeuf (Vache), Mouton, Cobaye, Chévre, Cheval, Avian, Âne et Hamster.

Aperçu rapide pour CD4 anticorps (ABIN6254232)

Highlights:

• High quality CD4 Anticorps primaire for the detection of CD4.
• Reliable product with high standard validation data

Antigène: CD4

Reactivité: Humain, Souris, Rat, Poulet, Singe, Chien, Porc, Lapin, Boeuf (Vache), Mouton, Cobaye, Chévre, Cheval, Avian, Âne, Hamster

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD4 anticorps

Fonction: Anti-CD4

Séquence: FHWKNSNQIK ILGNQGSFLT KGPSKLNDRA DSRRSLWDQG NFPLIIKNLK IEDSDTYICE VSQLELQDSG TWTCTVLQNQ KKVEFKIDIV VLAFQKASSI VYKKEGEQVE FSFPLAFTVE VEDQKEEVQL LVFGLTANSD THLLQGQSLT LTLESPPGSS PSVQCRSPRG KNIQGGKTLS KLTGSG

Specificité: Using spleen lysate detects a 52 kDa band by Western blot.

Attributs du produit: CD4 Molecule

Purification: Epitope affinity purified

Immunogène: Purified recombinant peptide derived from within 50 to 235 aa, corresponding to the external domain of human CD4 produced in E. coli.

Isotype: IgG

Informations sur le produit:

What can the CD4 Antibody ABIN6254232 be used for?: This polyclonal CD4 Antibody detects CD4. The CD4 Antibody has been validated for various applications and can be used for the detection of CD4 and derivatives by Western Blotting, Immunohistochemistry (Frozen Sections), Immunohistochemistry (Paraffin-embedded Sections).

What validation data is available for this CD4 Antibody?: The Anticorps primaire is referenced in 1 publications and is characterized by a proven, very high reliability. It has currently 6 product images that show its performance in a variety of applications. The product is currently available in 600 μg quantity. CD4 Antibody for the detection of CD4 and derivatives.

What is the function of CD4?: This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].

Information d'application

Indications d'application: WB:1:500-1:2,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Stockage

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: The antibody solution should be gently mixed before use.

Stock: 4 °C,-20 °C

Stockage commentaire: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Références pour anticorps anti-CD4 (ABIN6254232)

Helsby, Leader, Fenn, Gulsen, Bryant, Doughton, Sharpe, Whitley, Caunt, James, Pope, Kelly, Chalmers: "CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited." dans: BMC cell biology, Vol. 15, pp. 6, (2014) (PubMed).

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Sujet:

Goat polyclonal antibody to CD4. CD4 is a member of the immunoglobulin superfamily, a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and a receptor for the human immunodeficiency virus. This protein is expressed not only on the surface of T helper cells and regulatory T cells but also on monocytes, macrophages and dendritic cells. It functions to initiate or amplify the early phase of T-cell activation and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system.

CD4mut, CD4 antigen (p55), CD4 Receptor, T-cell surface antigen T4/Leu-3 and T-cell surface glycoprotein CD4 antibody.

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events