SNCA anticorps (pSer129)

N° du produit ABIN6254965

Cet anticorps anti-SNCA est un anticorps Lapin Polyclonal détectant SNCA dans WB, ELISA, IHC, IF et ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SNCA anticorps (pSer129) (ABIN6254965)

Antigène: SNCA (Synuclein, alpha (SNCA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNCA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-SNCA anticorps

Épitope: pSer129

Specificité: Phospho-Synuclein alpha (Ser129) Antibody detects endogenous levels of Synuclein alpha only when phosphorylated at Serine 129.

Homologie: Pig,Bovine,Horse,Rabbit,Dog,Chicken

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Synuclein alpha around the phosphorylation site of Ser129.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur SNCA

Antigène: SNCA (Synuclein, alpha (SNCA))

Autre désignation: SNCA

Sujet:

Description: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Gene: SNCA

Poids moléculaire: 18kDa

ID gène: 6622

UniProt: P37840

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity