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Cofilin anticorps (pSer3)

CFL1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated

Western blot analysis of extracts from Mouse muscle tissue,Hela cells,JK cells and Hela+H2o2 cells, using Phospho-Cofilin (Ser3) Antibody (af3232) at 1/1000 dilution. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human meningeal carcinomatosis(MC) tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human meningeal carcinomatosis(MC) tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human spleen tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human appendiceal tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat uterine tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining mouse testicular tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human liver tissue cells by ICC/IF. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human duodenum tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human skin tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat brain tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining mouse brain tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human vascular cancer tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat appendiceal tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human brain tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat ovarian tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human myosarcoma tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human esophageal carcinoma tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human glioma tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human pancreatic tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat gastric tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat kidney tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/200 staining human seminoma tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining mouse kidney tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat heart tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining mouse splenic tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining mouse lung tissue sections by IHC-P. (Cofilin anticorps (pSer3))

ABIN6267443 at 1/100 staining rat testicular tissue sections by IHC-P. (Cofilin anticorps (pSer3))

Western blot analysis of Cofilin phosphorylation expression in COLO205 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (Cofilin anticorps (pSer3))

29 images

N° du produit ABIN6255180

Fiche de données

Antigène Voir toutes Cofilin (CFL1) Anticorps

Cofilin (CFL1) (Cofilin 1 (CFL1))
Épitope
18

16

15

15

13

9

7

7

7

7

6

6

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer3
Reactivité
139

96

93

6

6

5

4

2

1

1

1

1
Humain, Souris, Rat
Hôte
143

10

2
Lapin
Anticorps secondaires appropriés
Clonalité
143

11
Polyclonal
Conjugué
73

11

11

8

7

5

4

4

4

4

4

4

3

3

3

3

3

1
Cet anticorp Cofilin est non-conjugé
Application
74

64

47

47

41

41

31

30

15

13

7

7

3

3

3

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité

Phospho-Cofilin (Ser3) Antibody detects endogenous levels of Cofilin only when phosphorylated at Serine 3.

Homologie

Pig,Bovine,Horse,Sheep,Dog

Purification

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène

A synthesized peptide derived from human Cofilin around the phosphorylation site of Ser3.

Isotype

IgG

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CFL1 Reactivité: Humain, Souris WB, IHC (p), FACS Hôte: Lapin Polyclonal RB20525 unconjugated

Indications d'application

WB 1:500-1:2000, IHC 1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption

12 months
Antigène

Cofilin (CFL1) (Cofilin 1 (CFL1))

Autre désignation

CFL1 (CFL1 Produits)

Synonymes

anticorps cfl1, anticorps xac1, anticorps xac2, anticorps cfl, anticorps cb86, anticorps sb:cb86, anticorps zgc:56501, anticorps wu:fb18a04, anticorps wu:fk77b03, anticorps 12/8, anticorps ADF, anticorps ADF/cofilin, anticorps Adf, anticorps CG4254, anticorps Cadf, anticorps D-cof, anticorps D61, anticorps Dmel\\CG4254, anticorps T8, anticorps Tsr, anticorps cofilin, anticorps cofilin/ADF, anticorps cofilin/actin depolymerizing factor homolog, anticorps l(2)03101, anticorps l(2)k03101, anticorps l(2)k05633, anticorps l(2)k13409, anticorps ntf, anticorps CFL, anticorps AA959946, anticorps Cof, anticorps CFL1, anticorps cofilin 1 (non-muscle) L homeolog, anticorps cofilin 1 (non-muscle), anticorps cofilin 1 (non-muscle), like, anticorps cofilin 1, anticorps twinstar, anticorps cofilin, anticorps cofilin 1, non-muscle, anticorps Contrafreeloading, anticorps cfl1.L, anticorps cfl1, anticorps cfl1l, anticorps CFL1, anticorps tsr, anticorps COF1, anticorps TSTA_042790, anticorps Cfl1, anticorps CFL

Sujet

Description: Binds to F-actin and exhibits  pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).
Gene: CFL1

Poids moléculaire

19kDa

ID gène

1072

UniProt

P23528

Pathways

Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events

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