CSNK1A1 anticorps (pTyr294)

N° du produit ABIN6256701

L’anticorps anti-CSNK1A1 Polyclonal Lapin est utilisé pour la détection de CSNK1A1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC, ELISA, IF et ICC.

Aperçu rapide pour CSNK1A1 anticorps (pTyr294) (ABIN6256701)

Antigène: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSNK1A1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-CSNK1A1 anticorps

Épitope: pTyr294

Specificité: Phospho-CK-1 alpha (Tyr294) Antibody detects endogenous levels of CK-1 alpha only when phosphorylated at PhoTyr294

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogène: A synthesized peptide derived from human Phospho-CK-1 alpha (Tyr294)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur CSNK1A1

Antigène: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Autre désignation: CK-1 alpha

Sujet:

Description: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).

Gene: CSNK1A1

Poids moléculaire: 38 kDa

ID gène: 1452

UniProt: P48729, Q8N752

Pathways: Signalisation WNT, Signalisation Hedgehog