IL-11 anticorps (N-Term)

N° du produit ABIN6257286

L’anticorps Lapin Polyclonal anti-IL-11 a été validé pour WB et ELISA. Il convient pour détecter IL-11 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IL-11 anticorps (N-Term) (ABIN6257286)

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-11 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL-11 anticorps

Épitope: N-Term

Specificité: IL11 Antibody detects endogenous levels of total IL11.

Homologie: Pig,Bovine,Horse,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human IL11, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Date de péremption: 12 months

Détails sur IL-11

Antigène: IL-11 (IL11) (Interleukin 11 (IL11))

Autre désignation: IL11

Sujet:

Description: Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

Gene: IL11

Poids moléculaire: 27 kDa

ID gène: 3589

UniProt: P20809

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion