PLCE1 anticorps
Aperçu rapide pour PLCE1 anticorps (ABIN6257434)
Antigène
Voir toutes PLCE1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- PLCE1 antibody detects endogenous levels of total PLCE1
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Réactivité croisée
- Humain, Souris
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- PLCE1 (Phospholipase C, epsilon 1 (PLCE1))
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Autre désignation
- PLCE1
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Sujet
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Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.
Gene: PLCE1
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ID gène
- 51196
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UniProt
- Q9P212
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Pathways
- EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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