PLCE1 anticorps

N° du produit ABIN6257434

Détail du produit anti-PLCE1 anticorps

Antigène: PLCE1 (Phospholipase C, epsilon 1 (PLCE1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLCE1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Specificité: PLCE1 antibody detects endogenous levels of total PLCE1

Réactivité croisée: Humain, Souris

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PLCE1

Antigène: PLCE1 (Phospholipase C, epsilon 1 (PLCE1))

Autre désignation: PLCE1 (PLCE1 Produits)

Synonymes: anticorps PLCE1, anticorps NPHS3, anticorps PLCE, anticorps PPLC, anticorps 4933403A21Rik, anticorps PLCepsilon, anticorps Plce, anticorps mKIAA1516, anticorps phospholipase C, epsilon 1, anticorps phospholipase C epsilon 1, anticorps PLCE1, anticorps plce1, anticorps Plce1

Sujet:

Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation.

Gene: PLCE1

ID gène: 51196

UniProt: Q9P212

Pathways: EGFR Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling