UBR1 anticorps (Internal Region)

N° du produit ABIN6258376

Cet anticorps anti-UBR1 Polyclonal Lapin (ABIN6258376) détecte spécifiquement UBR1 dans WB, ELISA, IF et ICC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour UBR1 anticorps (Internal Region) (ABIN6258376)

Antigène: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-UBR1 anticorps

Épitope: Internal Region

Specificité: UBR1 Antibody detects endogenous levels of total UBR1.

Homologie: Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human UBR1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur UBR1

Antigène: UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))

Autre désignation: UBR1

Sujet:

Description: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Gene: UBR1

Poids moléculaire: 36 kDa

ID gène: 197131

UniProt: Q8IWV7