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FZD9 anticorps (C-Term)

FZD9 Reactivité: Humain, Souris, Rat WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6258745
  • Antigène Voir toutes FZD9 Anticorps
    FZD9 (Frizzled Family Receptor 9 (FZD9))
    Épitope
    • 16
    • 15
    • 7
    • 7
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 77
    • 30
    • 21
    • 11
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 76
    • 1
    Lapin
    Clonalité
    • 77
    Polyclonal
    Conjugué
    • 37
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FZD9 est non-conjugé
    Application
    • 52
    • 36
    • 13
    • 13
    • 12
    • 8
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    FZD9 Antibody detects endogenous levels of total FZD9.
    Homologie
    Pig,Bovine,Sheep,Rabbit,Dog,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human FZD9, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product FZD9 Anticorps primaire
  • Indications d'application
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    FZD9 (Frizzled Family Receptor 9 (FZD9))
    Autre désignation
    FZD9 (FZD9 Produits)
    Synonymes
    anticorps CD349, anticorps FZD3, anticorps mfz9, anticorps Fz-9, anticorps cFz-9, anticorps fz11, anticorps fzd9, anticorps fzx, anticorps hm:zehl0603, anticorps zehl0603, anticorps zg11, anticorps frizzled class receptor 9, anticorps frizzled class receptor 9a, anticorps frizzled class receptor 9b, anticorps FZD9, anticorps Fzd9, anticorps fzd9a, anticorps fzd9b
    Sujet

    Description: Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity). Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway (By similarity). May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process (PubMed:27509850). During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. Positively regulates bone regeneration through non canonical Wnt signaling (By similarity).

    Gene: FZD9

    Poids moléculaire
    64 kDa
    ID gène
    8326
    UniProt
    O00144
    Pathways
    Signalisation WNT
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