Centriolin anticorps

N° du produit ABIN6260763

Détail du produit anti-Centriolin anticorps

Antigène: Centriolin (CNTRL)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Centriolin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: CEP110 Antibody detects endogenous levels of total CEP110

Réactivité croisée: Humain, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CEP110

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000 IHC 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur Centriolin

Antigène: Centriolin (CNTRL)

Autre désignation: CEP110 (CNTRL Produits)

Synonymes: anticorps CEP1, anticorps CEP110, anticorps FAN, anticorps bA165P4.1, anticorps Cep1, anticorps Cep110, anticorps 6720467O09Rik, anticorps AA968343, anticorps Cntrl, anticorps IB3/5, anticorps Ma2a8, anticorps b2b1468Clo, anticorps centriolin, anticorps CNTRL, anticorps Cntrl

Sujet:

Description: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).

Gene: CCP110

Poids moléculaire: 113kDa

ID gène: 9738

UniProt: O43303

Pathways: M Phase, SARS-CoV-2 Protein Interactome