CNGB3 anticorps (N-Term)

N° du produit ABIN6260909

Détail du produit anti-CNGB3 anticorps

Antigène: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNGB3 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: CNGB3 Antibody detects endogenous levels of total CNGB3.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CNGB3, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CNGB3

Antigène: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Autre désignation: CNGB3 (CNGB3 Produits)

Synonymes: anticorps ACHM1, anticorps CCNC2, anticorps CNG6, anticorps Cngbeta2, anticorps Cng6, anticorps RGD1565364, anticorps cyclic nucleotide gated channel beta 3, anticorps cyclic nucleotide gated channel beta 3, tandem duplicate 1, anticorps CNGB3, anticorps cngb3.1, anticorps Cngb3

Sujet:

Description: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

Gene: CNGB3

Poids moléculaire: 92 kDa

ID gène: 54714

UniProt: Q9NQW8