CNGB3 anticorps

N° du produit ABIN7227976

Cet anticorps Lapin Polyclonal détecte spécifiquement CNGB3 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour CNGB3 anticorps (ABIN7227976)

Antigène: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNGB3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CNGB3 anticorps

Fonction: Rabbit Anti-CNGB3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of CNGB3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human CNGB3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur CNGB3

Antigène: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Autre désignation: CNGB3

Sujet: Cyclic nucleotide-gated cation channel beta-3, Cone photoreceptor cGMP-gated channel subunit beta, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-3, CNG channel beta-3CNGB3 (Cyclic Nucleotide Gated Channel Beta 3) is a Protein Coding gene. Diseases associated with CNGB3 include Achromatopsia 3 and Stargardt Disease 1. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Activation of cAMP-Dependent PKA. CNGB encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

Poids moléculaire: 88kD

ID gène: 54714

UniProt: Q9NQW8