CRTC3 anticorps (Internal Region)

N° du produit ABIN6261047

Détail du produit anti-CRTC3 anticorps

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Épitope: Internal Region

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRTC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Specificité: CRTC3 Antibody detects endogenous levels of total CRTC3.

Homologie: Pig,Bovine,Sheep,Rabbit,Dog

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human CRTC3, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur CRTC3

Antigène: CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))

Autre désignation: CRTC3 (CRTC3 Produits)

Synonymes: anticorps torc3, anticorps MGC146372, anticorps 2610312F20Rik, anticorps 6332415K15Rik, anticorps AI429792, anticorps BC011210, anticorps TORC3, anticorps RGD1309666, anticorps TORC-3, anticorps CREB regulated transcription coactivator 3, anticorps CREB regulated transcription coactivator 3 L homeolog, anticorps CRTC3, anticorps crtc3, anticorps Crtc3, anticorps crtc3.L

Sujet:

Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Gene: CRTC3

Poids moléculaire: 76 kDa

ID gène: 64784

UniProt: Q6UUV7

Pathways: SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2