CRTC3 anticorps
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- Antigène Voir toutes CRTC3 Anticorps
- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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Reactivité
- Humain, Singe
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CRTC3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human CRTC3 expressed in E. coli.
- Clone
- 5G9
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
: "A new type of MAML2 fusion in mucoepidermoid carcinoma." dans: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).
: "
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Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
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- Antigène
- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
- Autre désignation
- CRTC3 (CRTC3 Produits)
- Synonymes
- anticorps torc3, anticorps MGC146372, anticorps 2610312F20Rik, anticorps 6332415K15Rik, anticorps AI429792, anticorps BC011210, anticorps TORC3, anticorps RGD1309666, anticorps TORC-3, anticorps CREB regulated transcription coactivator 3, anticorps CREB regulated transcription coactivator 3 L homeolog, anticorps CRTC3, anticorps crtc3, anticorps Crtc3, anticorps crtc3.L
- Sujet
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Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
Aliases: TORC3, FLJ21868, CRTC3
- Poids moléculaire
- 68 kDa
- ID gène
- 64784
- HGNC
- 64784
- Pathways
- SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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