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CRTC3 anticorps

CRTC3 Reactivité: Humain, Singe WB, IHC, ELISA, ICC Hôte: Souris Monoclonal 5G9 unconjugated
N° du produit ABIN969068
  • Antigène Voir toutes CRTC3 Anticorps
    CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
    Reactivité
    • 39
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Singe
    Hôte
    • 36
    • 3
    Souris
    Clonalité
    • 34
    • 5
    Monoclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CRTC3 est non-conjugé
    Application
    • 26
    • 13
    • 13
    • 10
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogène
    Purified recombinant fragment of human CRTC3 expressed in E. coli.
    Clone
    5G9
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    4°C, -20°C for long term storage
  • Nakayama, Miyabe, Okabe, Sakuma, Ijichi, Hasegawa, Nagatsuka, Shimozato, Inagaki: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." dans: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).

    Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: "A new type of MAML2 fusion in mucoepidermoid carcinoma." dans: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).

  • Antigène
    CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
    Autre désignation
    CRTC3 (CRTC3 Produits)
    Synonymes
    anticorps torc3, anticorps MGC146372, anticorps 2610312F20Rik, anticorps 6332415K15Rik, anticorps AI429792, anticorps BC011210, anticorps TORC3, anticorps RGD1309666, anticorps TORC-3, anticorps CREB regulated transcription coactivator 3, anticorps CREB regulated transcription coactivator 3 L homeolog, anticorps CRTC3, anticorps crtc3, anticorps Crtc3, anticorps crtc3.L
    Sujet

    Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

    Aliases: TORC3, FLJ21868, CRTC3

    Poids moléculaire
    68 kDa
    ID gène
    64784
    HGNC
    64784
    Pathways
    SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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