EIF2C3 anticorps (Internal Region)
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- Antigène Voir toutes EIF2C3 Anticorps
- EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
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Épitope
- Internal Region
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF2C3 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- EIF2C3 Antibody detects endogenous levels of total EIF2C3.
- Homologie
- Zebrafish,Bovine,Sheep,Rabbit,Dog,Chicken
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogène
- A synthesized peptide derived from human EIF2C3, corresponding to a region within the internal amino acids.
- Isotype
- IgG
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- Indications d'application
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
- Date de péremption
- 12 months
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- Antigène
- EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))
- Autre désignation
- AGO3 (EIF2C3 Produits)
- Synonymes
- anticorps EIF2C3, anticorps Eif2c3, anticorps Argonaute3, anticorps ago3, anticorps eif2c3, anticorps eif2c3b, anticorps si:dkey-3n22.3, anticorps AW048688, anticorps C130014L07Rik, anticorps ARGONAUTE 3, anticorps T19E23.8, anticorps T19E23_8, anticorps argonaute 3, RISC catalytic component, anticorps argonaute RISC catalytic component 3b, anticorps argonaute RISC catalytic subunit 3, anticorps argonaute RISC catalytic component 3, anticorps ARGONAUTE 3, anticorps AGO3, anticorps Ago3, anticorps ago3b
- Sujet
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Description: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.
Gene: AGO3
- Poids moléculaire
- 97 kDa
- ID gène
- 192669
- UniProt
- Q9H9G7
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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