HECTD1 anticorps (Internal Region)

N° du produit ABIN6262200

L’anticorps anti-HECTD1 Polyclonal Lapin est utilisé pour la détection de HECTD1 dans des échantillons de Humain, Souris, Rat et Singe. Il a été validé pour WB et IHC.

Aperçu rapide pour HECTD1 anticorps (Internal Region) (ABIN6262200)

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HECTD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HECTD1 anticorps

Épitope: Internal Region

Fonction: HECTD1 Antibody

Specificité: HECTD1 Antibody detects endogenous levels of total HECTD1

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human HECTD1, corresponding to a region within the internal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-3000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Détails sur HECTD1

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Autre désignation: HECTD1

Sujet:

Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion. Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells may impair their emigration and may be essential for the correct development of the cranial neural folds and neural tube closure.

Gene: HECTD1

Poids moléculaire: 289kDa

ID gène: 25831

UniProt: Q9ULT8

Pathways: Tube Formation, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2