HECTD1 anticorps

N° du produit ABIN7074186

L’anticorps anti-HECTD1 Polyclonal Lapin est utilisé pour la détection de HECTD1 dans des échantillons de Rat. Il a été validé pour IHC et IF.

Aperçu rapide pour HECTD1 anticorps (ABIN7074186)

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HECTD1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-HECTD1 anticorps

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse HECTD1

Information d'application

Indications d'application: IHC/IF (R) 1:1000-1:2000/1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur HECTD1

Antigène: HECTD1 (HECT Domain Containing 1 (HECTD1))

Autre désignation: HECTD1

Sujet: HECTD1 (E3 ubiquitin-protein ligase, which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates . Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion . Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells impairs their emigration and is consequently essential for the correct development of the cranial neural folds and neural tube closure.It is also involved in sporadic Parkinson's disease.

UniProt: Q69ZR2

Pathways: Tube Formation, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2