NEDD8 anticorps

N° du produit ABIN6263583

L’anticorps Lapin Polyclonal anti-NEDD8 a été validé pour WB, IHC, ELISA, IF et ICC. Il convient pour détecter NEDD8 dans des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour NEDD8 anticorps (ABIN6263583)

Antigène: NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEDD8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-NEDD8 anticorps

Specificité: NEDD8 antibody detects endogenous levels of total NEDD8

Réactivité croisée: Humain, Singe, Souris, Rat (Rattus)

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human NEDD8

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C.Stable for 12 months from date of receipt

Date de péremption: 12 months

Détails sur NEDD8

Antigène: NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))

Autre désignation: NEDD8

Sujet:

Description: Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

Gene: NEDD8

Poids moléculaire: 85kDa

ID gène: 4738

UniProt: Q15843

Pathways: Ubiquitin Proteasome Pathway