RRM2 anticorps (C-Term)

N° du produit ABIN6264868

Cet anticorps anti-RRM2 est un anticorps Lapin Polyclonal détectant RRM2 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour RRM2 anticorps (C-Term) (ABIN6264868)

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RRM2 anticorps

Épitope: C-Term

Specificité: RRM2 Antibody detects endogenous levels of total RRM2.

Homologie: Bovine,Horse,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogène: A synthesized peptide derived from human RRM2, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20 °C. Stable for 12 months from date of receipt.

Date de péremption: 12 months

Références pour anticorps anti-RRM2 (ABIN6264868)

Xia, Wang, Song, Meng, Huang, Huang: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).

Détails sur RRM2

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Autre désignation: RRM2

Sujet:

Description: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.

Gene: RRM2

Poids moléculaire: 45kDa

ID gène: 6241

UniProt: P31350

Pathways: Mitotic G1-G1/S Phases