WASF1 anticorps (Internal Region)
Aperçu rapide pour WASF1 anticorps (Internal Region) (ABIN6266012)
Antigène
Voir toutes WASF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- WAVE1 Antibody detects endogenous levels of total WAVE1.
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Homologie
- Pig,Bovine,Horse,Rabbit,Dog,Chicken
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Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogène
- A synthesized peptide derived from human WAVE1, corresponding to a region within the internal amino acids.
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Isotype
- IgG
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Indications d'application
- WB 1:1000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C. Stable for 12 months from date of receipt.
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Date de péremption
- 12 months
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- WASF1 (WAS Protein Family, Member 1 (WASF1))
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Autre désignation
- WASF1
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Sujet
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Description: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).
Gene: WASF1
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Poids moléculaire
- 70kDa
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ID gène
- 8936
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UniProt
- Q92558
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Pathways
- Signalisation RTK, Regulation of Actin Filament Polymerization
Antigène
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